How to Find the Best Protein Powder for ICU Patients

📌 Overview and Key Takeaways

This is a Certified Nutrition Coach’s guide on how to find the best protein powder for ICU patients.

Discover how to safely meet your protein needs while in the ICU.

drink wholesome founder
Last Updated
Jul 21, 2026
Author and Medical Reviewer

Written by Jack, CNC

Jack is a National Academy of Sports Medicine Certified Nutrition Coach.

Disclaimer: This communication is for general informational purposes only and is not a substitute for personalized medical advice. Consult a licensed healthcare professional before making changes to your diet.

Protein Powder for ICU Patients

Are Protein Powder Good for ICU Patients?

Adequate protein intake is important for maintaining muscle mass, promoting wound healing, and supporting immune function.

It is therefore unsurprising that research shows increased dietary protein intake improves outcomes in the context of critical illness (J Clin Med, 2019).

In critically ill patients who survive hospitalization, higher daily protein intake during hospitalization is associated with decreased mortality following discharge from the hospital.

Moreover, increased protein intake following the acute phase of illness translates improves the retention of muscle and muscle strength, both of which assist with recovery.

Keep in mind that intensive care unit (ICU) patients should try to get as much protein as they can from protein sources like dairy, eggs, fish, legumes, nuts, meat, and seeds.

Getting enough protein this way can be hard, however, especially for patients with dietary restrictions or difficulty swallowing, which is where protein powder can help.

Protein powder can be mixed with just milk or water to make a protein shake, or added to smoothies, oatmeal, and other recipes.

This convenience and versatility is hard to beat.

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How Much Protein Do ICU Patients Need?

The protein needs of ICU patients vary based on their condition, age, weight, and underlying health issues.

That said, the general guidelines for protein intake in ICU patients are as follows:

  1. General Adult ICU Patients: The American Society for Parenteral and Enteral Nutrition (ASPEN) recommends that critically ill adult patients receive 1.2 to 2 grams of protein per kilogram of body weight per day (JPEN J Parenter Enteral Nutr, 2016), which is twice as much as what healthy adults need!
  2. Obese ICU Patients: For obese patients, protein needs might be increased 2 to 2.5 grams of protein per kilogram of ideal body weight per day.
  3. Patients with Severe Trauma or Burns: Patients with severe trauma, burns, or significant wounds may require even more protein, sometimes as much as 2.5 grams per kilogram of body weight per day.

Note that these recommendations are only general; the specific protein requirements for an ICU patient should be determined by their healthcare team.

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What Is the Best Protein Powder for ICU Patients?

The type of protein powder that you add to your diet is not particularly important.

That is, as long as you are eating a balanced diet (getting protein from a variety of sources), any type of protein (egg, pea, whey, etc.) can help you meet your total daily protein needs.

Not all protein powders are created equal, however.

Many protein shakes and powders contain ingredients that might contribute to long-term health problems and worse outcomes for ICU patients.

Among the most problematic ingredients are food additives.

🚫 Avoid Food Additives

Regularly eating emulsifiers, thickeners, artificial sweeteners, and other ultra-processed additives can alter the composition of your gut microbiome (North Clin Istanb, 2019).

These shifts, known as gut dysbiosis, have been associated with worse outcomes for critically ill patients (Curr Opin Crit Care, 2025).

Specifically, dysbiosis increases susceptibility to infections, promotes immune dysfunction, and drives organ failure.

⚠️ Here is a list of the most common additives in protein shakes and powders:

  • acacia fiber
  • acacia gum
  • acesulfame potassium
  • artificial flavors
  • ascorbic acid
  • aspartame
  • calcium carbonate
  • carrageenan
  • cellulose gum
  • dextrin
  • dicalcium phosphate
  • dipotassium phosphate
  • erythritol
  • gellan gum
  • guar gum
  • gum arabic
  • inulin
  • locust bean gum
  • maltitol
  • maltodextrin
  • mono- and diglycerides
  • ‘natural’ flavors
  • rice bran extract
  • rice dextrin
  • rice hulls
  • rosemary extract
  • silica
  • silicon dioxide
  • sodium alginate
  • soluble corn fiber
  • sorbitol
  • soy lecithin
  • sucralose
  • sunflower lecithin
  • tocopherols
  • tricalcium phosphate
  • xanthan gum
  • xylitol
  • zinc oxide

As a rule of thumb, if you cannot find it in nature or make it at home, it is probably a food additive.

🚫 Avoid Protein Concentrates and Isolates

I also recommend avoiding protein concentrates and isolates.

Most protein shakes and powders are made from one or both of these ultra-processed protein sources, which have been mechanically and/or chemically stripped of everything but the protein.

This includes the enzymes, fiber, and other natural digestive aids that help you break them down.

You therefore might not digest them in the same way that you do whole foods, which could affect your gut health.

For example, one study shows that regularly consuming protein concentrates and isolates might disrupt your gut microbiome (Nutrients, 2018).

Another study shows that it could cause the formation of toxic byproducts in your gut (Mol Nutr Food Res, 2024).

Although further research is needed, you can play it safe by choosing protein shakes and powders made from minimally-processed protein sources like egg whites and almonds.

Our customers find them to be more gut-friendly.

Order Samples to see for yourself.

Sources

  1. Journal of Clinical Medicine (J Clin Med). Protein Intake, Nutritional Status and Outcomes in ICU Survivors: A Single Center Cohort Study. 2019.
  2. Journal of Parenteral and Enteral Nutrition (JPEN J Parenter Enteral Nutr). Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Adult Critically Ill Patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.). 2016.
  3. Northern Clinics of Istanbul (North Clin Istanb). Food additives and microbiota. 2019.
  4. Current Opinion in Critical Care (Curr Opin Crit Care). Gut microbiota and its impact on critical illness.. 2025.
  5. Nutrients (Nutrients). Effect of a Protein Supplement on the Gut Microbiota of Endurance Athletes: A Randomized, Controlled, Double-Blind Pilot Study. 2018.
  6. Molecular Nutrition & Food Research (Mol Nutr Food Res). In Vitro Fermentation of Animal and Plant Protein Isolates by the Human Gut Microbiota Under High and Low Carbohydrate Conditions.. 2024.

Editorial Guidelines


This article was written by a Certified Nutrition Coach and reviewed by a Registered Dietitian. We rely on peer-reviewed research and trusted medical sources, and regularly update our content to ensure accuracy and clarity.

Frequently asked questions

Who Is Drink Wholesome for?

Drink Wholesome makes protein powder for sensitive stomachs, GERD, IBS, and other gut issues. It’s suitable for most food sensitivities, including lactose intolerance, and won’t cause side effects like bloating, constipation, and reflux.

Why Is Drink Wholesome Good for Sensitive Stomachs?

Drink Wholesome is the best protein powder for sensitive stomachs because it’s additive, dairy, and gluten-free. It’s also made from minimally-processed protein sources like egg whites and almonds. Other protein powders are made from ultra-processed protein concentrates and isolates, which look nothing like real food.

What’s the Difference Between Protein Powder and Meal Replacement Powder?

Drink Wholesome makes gut-friendly Protein Powders and Meal Replacement Powders. Protein powder is high in protein and low in everything else, whereas meal replacement powder contains fats, carbs, fiber, and protein because it’s intended to replace the nutritional value of a balanced meal.

What’s the Difference Between Almond, Collagen, and Egg White Protein?

We make three types of stomach-friendly Protein Powder: Collagen Protein Powder, Egg White Protein Powder, and Vegan Almond Protein Powder. As long as you get protein from a variety of sources, any type of protein can help you meet your total daily protein needs. In other words, for someone with a balanced diet, there is no advantage to consuming one type of protein over another. Order Samples to see which type you like the most.

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If you’re wondering which Drink Wholesome product is best for you, ask our Certified Nutrition Coach. For personalized medical advice, consult your healthcare provider.

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High Protein Blueberry Pancakes

PREP TIME

5 min

COOK TIME

5 min

SERVES

2

Ingredients
  • ¼ cup Drink Wholesome
  • ⅓ cup flour
  • 2 egg whites
  • ¼ cup plant milk
  • 1 tbsp nut butter
  • 2 tbsp maple syrup
  • 1 cup blueberries
Instructions

In a blender, combine the egg whites, milk, ¼ cup blueberries, and almond butter. Pour the mixture into a small mixing bowl and add the protein powder and flour. Whisk until smooth. Pour ⅓ cup batter onto a heated and greased (or non-stick) pan to form pancakes. Cook each side for 2-3 minutes. This recipe makes 4-5 pancakes. Then, in a small saucepan, heat ¾ cup blueberries and the maple syrup over medium heat, stirring occasionally, for about 8 minutes. Plate the pancakes and spoon blueberry jam on top.