What Is the Best Low Histamine Protein Powder?


Are you looking for the best low histamine protein powder? Discover how to safely supplement your protein intake with histamine intolerance.

Low Histamine Protein Powder

Is Protein Powder Good for a Low Histamine Diet? 


Histamine is a chemical that acts as a neurotransmitter (chemical messenger).

Among other things, it triggers the release of stomach acid and causes inflammation as part of a local immune response.

Histamine intolerance is a disorder associated with the inability to fully metabolize (break down) histamine, which is both made by the body and taken in from food.

Histamine that is not broken down builds up in the blood, causing symptoms like headaches, nasal congestion, fatigue, hives, and digestive issues.

Common causes of histamine intolerance include:

  1. Medications or foods that inhibit the function or production of the gastrointestinal (GI) enzyme diamine oxidase (DAO)
  2. Foods that trigger histamine release
  3. GI disorders such as inflammatory bowel disease (IBS), leaky gut syndrome, and small intestinal bacterial overgrowth (SIBO).

Note that disorders like IBS can cause inflammation in the gut, which may impair DAO function and production.

Gut inflammation, in turn, can cause excessive histamine production.

And excessive histamine production paired with impaired enzyme activity can lead to increased histamine absorption and accumulation in the bloodstream.

In other words, an unhealthy gut could be the main driver of histamine intolerance.

a man and a woman making a protein shake with drink wholesome protein powder

The low histamine diet aims to reduce symptoms of histamine intolerance by avoiding histamine-rich and histamine-releasing foods.

Research shows that reducing histamine-rich foods in the diet dramatically reduces symptoms.

Foods high in histamine include alcohol and other fermented beverages, dairy products, and processed and fried foods.

Examples of histamine-releasing foods include pineapple, shellfish, and tomatoes.

Keep in mind that the low-histamine diet is not a histamine intolerance treatment, but rather a band-aid for symptom relief.

This is why addressing the underlying causes of histamine intolerance, which might a be GI disorder like IBS, leaky gut, or SIBO, is so important.

Moreover, because each of these conditions can be managed through diet, picking the right protein powder can make a huge difference.

a protein shake made with drink wholesome protein powder

What Is the Best Protein Powder for Histamine Intolerance?


Histamine tolerance can vary greatly from person to person, so a protein powder that works for one person might not work for someone else.

That said, there are several guidelines that anyone with histamine intolerance can follow.

Egg white protein, hemp protein, and rice protein are all low in histamine, so it is best to start with one of these protein sources.

Then, make sure your protein powder does not contain any food additives, as ingredients like these can be problematic for individuals with histamine intolerance.

Part of the reason why food additives like emulsifiers and thickeners are so problematic is that they can alter the composition of your gut microbiome.

This can lead to gut dysbiosis, or an imbalance in gut bacteria, which has been linked to the onset and progression of histamine intolerance.

Here is a list of the most common food additives in protein supplements:

  • acacia fiber
  • acacia gum
  • acesulfame potassium
  • artificial flavors
  • ascorbic acid
  • aspartame
  • calcium carbonate
  • carrageenan
  • cellulose gum
  • dextrin
  • dicalcium phosphate
  • dipotassium phosphate
  • erythritol
  • gellan gum
  • guar gum
  • gum arabic
  • inulin
  • locust bean gum
  • maltitol
  • maltodextrin
  • mono- and diglycerides
  • ‘natural’ flavors
  • rice bran extract
  • rice dextrin
  • rice hulls
  • rosemary extract
  • silica
  • silicon dioxide
  • sodium alginate
  • soluble corn fiber
  • sorbitol
  • soy lecithin
  • sucralose
  • sunflower lecithin
  • tocopherols
  • tricalcium phosphate
  • xanthan gum
  • xylitol
  • zinc oxide

Basically, if you could not find an ingredient in nature or make it at home, it should not be in your protein powder. 

Avoid Protein Concentrates and Isolates

You should also avoid protein concentrates and isolates.

Most protein supplements are made from protein concentrates and isolates, which have been mechanically and/or chemically stripped of everything but the protein.

This includes the enzymes, fiber, and other natural digestive aids that help your gut break them down.

You therefore do not digest them in the same way that it does whole foods, which can affect everything from satiety to gut health.

In fact, studies show that regularly eating protein concentrates and isolates can disrupt your gut microbiome and cause the formation of toxic byproducts in your gut.

So, pending further research, stick to whole food protein sources if you suffer from histamine intolerance.

Drink Wholesome Is the Best Low Histamine Protein Powder

Finding a protein supplement free from food additives and protein concentrates and isolates is hard.

In fact, 99% of protein supplements contain one or more of these problematic ingredients, which is why we created Drink Wholesome.

We make the best protein powder for histamine intolerance because we use a short list of simple ingredients.

Our Ingredients

egg whites

egg whites

coconut

coconut

vanilla

vanilla

monk fruit

monk fruit

NOT Our Ingredients

  • acacia gum

  • acesulfame potassium

  • artificial flavors

  • carrageenan

  • erythritol

  • guar gum

  • inulin

  • maltodextrin

  • 'natural' flavors

  • silica

  • soy lecithin

  • sucralose

  • xanthan gum

  • xylitol

Note that instead of using protein concentrates or isolates, we use whole food protein sources like egg whites, which are easier to digest and absorb.

It follows that our customers experience fewer digestion problems with our Protein Powder than with any other type of protein supplement.

Order Samples to see for yourself.

Reviews

Gabriella

3 weeks ago

Verified Purchase As someone who has struggled with chronic conditions for 10+ years, getting in nutrient-dense foods is big part of how I care for my body. Finding options that are tasty and convenient is difficult. And I am always trying to eat enough in order to maintain my weight. Providers consistently recommend smoothies/shakes. I have tried so many over the years and each time the GI symptoms are intense or the flavor is awful! Since finding Drink Wholesome, I have finally been able to incorporate higher protein smoothies and shakes without the digestive upset. As a result, I have been able to maintain my weight more easily and even gain some beneficial weight. digestive issues

For Egg White Protein Powder

Gayle

2 months ago

Verified Purchase Drink Wholesome is really the best handful of ingredients protein powder that didnt give me any stomach issues at all. Anyone who has had bloat, etc should try this protein powder. I’ve been making smoothies since April 2025 and no problems at all. bloating

For Egg White Protein Powder

Matt

2 months ago

Verified Purchase After trying so many protein options and trying to live well with IBS on the go and staying fit and healthy in my 50s, I can honestly say what you are doing at Drink Wholesome is great. Keep up the great work, keep it simple and clean, and keep it positive like you have been. It’s refreshing and it works. Thank you. IBS

For Egg White Protein Powder

Frequently asked questions

Who is Drink Wholesome for?

Drink Wholesome is the best protein powder for sensitive stomachs. Because it’s made from a short list of simple ingredients, it’s also a great option for anyone who wants to avoid artificial and ultra-processed ingredients – including kids, seniors, and moms.

Why is Drink Wholesome easy to digest?

No Dairy 

Drink Wholesome is made without whey and casein, which contain lactose, a sugar most people can’t fully digest. Dairy-based proteins, especially casein, also form a gel-like substance in your stomach, which can upset sensitive stomachs.

No Additives

Drink Wholesome is made without food additives. Regularly eating artificial sweeteners, emulsifiers, thickeners, and other additives can cause digestive issues and even long-term gut health problems.

Whole Food Protein

Drink Wholesome is made from whole food protein sources like almonds and egg whites. Unlike ultra-processed protein concentrates and isolates, which have been stripped of fiber, enzymes, and other natural digestive aids, whole foods are easy to break down and absorb.

Collagen vs egg white vs almond protein powder?

We make three types of Protein Powder for sensitive stomachs: Collagen Protein Powder, Egg White Protein Powder, and Vegan Almond Protein Powder. As long as you eat a balanced diet (get protein from a variety of sources), any type of protein powder can help you meet your protein needs. So just pick the type that best suits your personal preferences.

Ask our dietitian.

If you’re wondering which of our products is best for you, ask our registered dietitian. He’ll reply via email within 24 hours.

Ask Our Dietitian
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High Protein Blueberry Pancakes

PREP TIME

5 min

COOK TIME

5 min

SERVES

2

Ingredients
  • ¼ cup Drink Wholesome
  • ⅓ cup flour
  • 2 egg whites
  • ¼ cup plant milk
  • 1 tbsp nut butter
  • 2 tbsp maple syrup
  • 1 cup blueberries
Instructions

In a blender, combine the egg whites, milk, ¼ cup blueberries, and almond butter. Pour the mixture into a small mixing bowl and add the protein powder and flour. Whisk until smooth. Pour ⅓ cup batter onto a heated and greased (or non-stick) pan to form pancakes. Cook each side for 2-3 minutes. This recipe makes 4-5 pancakes. Then, in a small saucepan, heat ¾ cup blueberries and the maple syrup over medium heat, stirring occasionally, for about 8 minutes. Plate the pancakes and spoon blueberry jam on top.

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